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  • itor's Summary Abstract Full Text PDF Epigenomics of human CD8 T cell differentiation and aging By David M.
  • . . . Access Restricted Access Genome-wide epigenetic profiling defines the transcriptional networks involved in T cell aging
  • . . . age-dependent degenerative disorders such as cancer, neurodegeneration and tissue atrophy, and in accelerated aging .
  • . . . drug candidate for preventing and treating diverse neurodegenerative pathologies, and may promote healthy aging . Introduction Various neurodegenerative conditions are associated with the progressive accumulation of damaged, dysfunctional proteins that can act as cellular toxins 1 , 2 , 3 , 4 , 5
  • . . . T-cell populations recruited to the CNS across the blood-CSF barrier accelerate many of the deleterious signs of aging 18 with type-1 interferon signaling being implicated in AD 19 .
  • . . . neuro-inflammation state that clears amyloid, but enhanced cytokine load combined with the deleterious effects of aging may worsen disease pathology
  • . . . Facebook Twitter Google YouTube RSS Public Health The Hunger Gains: Extreme Calorie-Restriction Diet Shows Anti-Aging Results A new study shows five days of hunger a month may reduce risk factors for aging and age-related diseases By Richard Conniff on February 16, 2017 Share on Facebook Share on Twitter Share on Reddit Email Print Share . . .
  • Laboratory research has repeatedly demonstrated the anti-aging value of calorie restriction, often called CR, in animals from nematodes to rats—with the implication that the same might be true for humans
  • . . . fat is more likely to form free radicals by lipid peroxidation — which can lead to cancer and may accelerate aging .
  • Lipid peroxidation and free radicals can cause cancer and may accelerate aging . High rates of lung cancer among women in China have been associated with lipid peroxidized oils in fumes from cooking polyunsaturated vegetable oils in a wok [*12]
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  • adline for Submission: September 30, 2017 Mitochondria Dysfunction in Aging and Metabolic Diseases.
  • . . . missense variants 2016 November 1 Acute kidney injury induces hallmarks of polycystic kidney disease 2016 October 1 Aging-associated renal disease in mice is fructokinase dependent 2016 October 1 Articles in Press Endothelial colony forming cells ameliorate endothelial dysfunction via secreted factors following ischemia-reperfusion injury.
  • . . . and podocyte progenitors Hydrodynamic gene delivery in the kidney Calls for Papers Most Cited Most Read Imaging techniques in renal (patho)physiology research - Submission Deadline June 30, 201 7 Inflammation and Inflammatory Mediators in Kidney Disease - Submission Deadline June 30, 201 7 Mechanism and treatment of renal fibrosis . . .
  • . . . Feb 2017 : e1601833 Open Access CCBY-NC Age-associated molecular changes are deleterious and causally linked with aging and may affect life span through diet.
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